Great thread. We have just started using OnTime in a non-software related industry. So far, here is how I have set it up. 3 of the 4 main tabs have been renamed for how we track things.

As shown below I have divided projects into 3 main categories, Company Wiki just for sharing internal info, External Projects which means projects for Clients, and Internal Projects for things like "Develop New Product Line".

For Client projects I am than dividing them into phases, which for the purposes of posting a screen shot here without showing private company info I just created a phony project and gave the phases generic names. I am trying to prevent too many levels under a project, so for now we go no deeper than phase.

If I was to name the single thing I love about OnTime so far, it is that due to the way it is structured, it gives me a mechanism for tracking countless tasks *without* having a huge monolithic unmanageable task list, which is the weakness of almost every other program I have ever evaluated or used. For instance, we are going to use the Tasks section to track major day to day tasks, while using the Punch List section to track the hundreds of small items we need to stay on top of on each project. OnTime provide so many tools even above and beyond the primary tabs to easily categorize, group and and manage tasks that I am finding it the best tasking/tracking tool I have ever encountered.
I'd really like to see more posts in this thread as well as any suggestions about how we might better utilize OnTime.
Thanks